{"title":"Adipeau","description":null,"products":[{"product_id":"volume-cream-by-adipeau","title":"Crema volumizzante di Adipeau","description":"\u003cdiv\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003ch1 class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cmeta charset=\"utf-8\"\u003eRipristina il volume perduto dall'interno.\u003c\/h1\u003e\n\u003ch2 class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cmeta charset=\"utf-8\"\u003e\u0026nbsp;La crema volumizzante è formulata attorno a due principi attivi validati in studi su adipociti umani condotti presso il Karolinska Institute.\u003c\/h2\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eSotto la superficie della pelle si trova uno strato di cellule adipose che la maggior parte dei prodotti per la cura della pelle non prende in considerazione. Questo strato di grasso dermico sostiene la struttura del viso, stimola i fibroblasti a produrre collagene ed elastina e conferisce alla pelle la sua naturale elasticità e morbidezza. Con l'età, l'esposizione al sole e la vita quotidiana, questo tessuto perde la sua funzionalità. Le cellule rimanenti si ingrossano e diventano meno attive. Quelle che dovrebbero sostituirle non arrivano. Il risultato è una progressiva perdita dell'impalcatura interna che mantiene il viso tonico.\u0026nbsp;\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eLa crema volumizzante Adipeau è stata sviluppata per affrontare questa causa principale. Agisce all'interno dello strato adiposo dermico utilizzando due principi attivi clinicamente testati per favorire la rigenerazione delle cellule adipose: il naturale rinnovamento degli adipociti sani, piccoli e funzionali che costituiscono la struttura portante della pelle.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eGli acidi grassi a catena lunga (LCFA), derivati dall'olio di semi di cartamo biologico (Carthamus Tinctorius), sono agonisti naturali del PPARγ. Essi segnalano ai precursori immaturi delle cellule adipose di maturare in adipociti sani e funzionali, supportando la rigenerazione del volume dermico perduto. Gli LCFA penetrano nella pelle attraverso la via transfollicolare, raggiungendo la profondità in cui si trovano le cellule adipose dermiche.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eI polimetossiflavonoidi (PMF), derivati dallo zenzero nero selvatico (Kaempferia Parviflora), agiscono in modo complementare. Stimolano la proliferazione delle cellule adipose immature e riducono le dimensioni di quelle mature e ipertrofiche, creando le condizioni per una popolazione più densa di cellule più piccole e sane. Negli studi preclinici, la combinazione di entrambi i principi attivi ha raddoppiato il numero di cellule adipose senza un aumento delle dimensioni medie delle cellule, a conferma di una reale rigenerazione tissutale.\u003c\/p\u003e\n\u003ch2 class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eGli effetti visibili: distribuzione del volume più uniforme, riduzione della texture a rughe, pori meno visibili e maggiore luminosità per una pelle ben nutrita dall'interno.\u003c\/h2\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Adipeau","offers":[{"title":"Default Title","offer_id":53290080764241,"sku":"DPR-ADP-VC","price":78.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0862\/5748\/files\/adipeau_volume_cream_depuravita.jpg?v=1773477514"},{"product_id":"strength-gel-by-adipeau","title":"Strength Gel by Adipeau","description":"\u003ch1\u003e\n\u003cmeta charset=\"utf-8\"\u003e \u003cmeta charset=\"utf-8\"\u003eClinically confirmed. Firms sagging skin and reduces cellulite.\u003cbr\u003e\n\u003c\/h1\u003e\n\u003ch2\u003e\n\u003cmeta charset=\"utf-8\"\u003eIn a clinical study, 100% of expert reviewers confirmed visible cellulite improvement after 12 weeks.\u003c\/h2\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eSagging, laxity, cellulite and crepe are not simply signs of volume loss. They are signs of a dermal fat layer where cells have grown too large, lost their structural function, and begun pulling the skin downward. Most firming products address the surface of this problem. The Strength Gel addresses the source. \u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eFormulated as a silicone gel with liposomal carriers for deep penetration, the Strength Gel delivers Kaempferia Parviflora extract directly to the dermal fat layer via the transfollicular route. There it performs two actions simultaneously: it reduces the size of enlarged, hypertrophic fat cells through direct lipolytic activity, and it stimulates the proliferation of new, small, healthy fat cell precursors. The result is a shift from fewer, oversized cells to more, smaller ones, which restores the tissue's structural stiffness, anti-inflammatory capacity, and ability to support collagen and elastin production above. \u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eThe gel also functions as a skin protectant, forming a light breathable barrier that soothes the skin for hours.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eIt is the recommended starting point in the Adipeau protocol. Use the Strength Gel alone for the first 4 to 6 weeks before adding the Volume Cream. The lifting effect and increased suppleness that develop during this phase are markers that the dermal structure is responding.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2 class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eHow It works?\u003c\/h2\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eThe primary active in the Strength Gel is Kaempferia Parviflora Rhizome Extract, a source of polymethoxyflavonoids (PMFs) with documented lipolytic and adipogenic activity. PMFs act on the PPARγ pathway that governs fat cell health. In the skin, they access dermal adipocytes via the hair follicle, delivering their action at the depth where firmness originates. \u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eIn Karolinska Institute preclinical work using 3D human adipocyte tissue models, Kaempferia Parviflora extract applied to hypertrophic fat tissue doubled fat cell number while reducing average cell size by over 40%. This is the biological profile of tissue regeneration: more cells, each smaller and healthier, capable of supporting the skin from within. \u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eMacadamia Ternifolia Seed Oil provides additional lipolytic and anti-inflammatory support. Cucumber extract soothes and calms local inflammation. Glycerin and dimethicone polymers provide the skin-protective function that makes the gel suitable for continuous use on areas of repeated movement such as the neck, knees, stomach, underarms and inner arms.\u003c\/p\u003e\n\u003ch2 class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eClinical Evidence\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eKarolinska Institute in-vitro study\u003c\/strong\u003e In models of hypertrophic human fat tissue, Kaempferia Parviflora Rhizome Extract doubled fat cell number and reduced average cell size by over 40%. Gene expression analysis confirmed activation of lipolytic pathways, stimulation of fat cell proliferation, and suppression of inflammatory and metabolic dysfunction signals. Pre-publication manuscript available on request.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eCellulite Appearance Clinical Study\u003c\/strong\u003e 17 participants with mild, moderate and severe cellulite applied the gel twice daily for 12 weeks. Standardised before-and-after photographs were evaluated by four independent blinded health professionals.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eAcross all images, at least two of four raters correctly identified the before image as more severe in 100% of cases. At least three of four agreed in 87.5% of cases. All four agreed in 75% of cases. In participants with moderate to severe cellulite, at least three of four raters agreed in 100% of cases, and all four agreed in 83%.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eSupporting references\u003c\/strong\u003e PMFs from Kaempferia Parviflora, lipolytic activity in vitro and in vivo: \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24629599\/\" class=\"underline underline underline-offset-2 decoration-1 decoration-current\/40 hover:decoration-current focus:decoration-current\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/24629599\/\u003c\/a\u003e \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30214264\/\" class=\"underline underline underline-offset-2 decoration-1 decoration-current\/40 hover:decoration-current focus:decoration-current\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/30214264\/\u003c\/a\u003e PMFs from Kaempferia Parviflora, pro-adipogenic activity: \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22687402\/\" class=\"underline underline underline-offset-2 decoration-1 decoration-current\/40 hover:decoration-current focus:decoration-current\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/22687402\/\u003c\/a\u003e Small adipocyte size inversely correlated with skin sagging: \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20637003\/\" class=\"underline underline underline-offset-2 decoration-1 decoration-current\/40 hover:decoration-current focus:decoration-current\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/20637003\/\u003c\/a\u003e Dermal adipocytes abundant in reticular dermis: \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24841073\/\" class=\"underline underline underline-offset-2 decoration-1 decoration-current\/40 hover:decoration-current focus:decoration-current\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/24841073\/\u003c\/a\u003e \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29603400\/\" class=\"underline underline underline-offset-2 decoration-1 decoration-current\/40 hover:decoration-current focus:decoration-current\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/29603400\/\u003c\/a\u003e\u003c\/p\u003e","brand":"Adipeau","offers":[{"title":"Default Title","offer_id":53290514547025,"sku":"DPR-ADP-SG","price":78.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0862\/5748\/files\/adiepau_strenght_gel_depuravita.jpg?v=1773479661"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0862\/5748\/collections\/Adipeau_combeau_depuravita_jpg.webp?v=1785403483","url":"https:\/\/depuravita.com\/it-it\/collections\/adipeau.oembed","provider":"Depuravita","version":"1.0","type":"link"}